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Bay R 1531
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Bay R 1531 : ウィキペディア英語版
Bay R 1531

Bay R 1531 is a tricyclic tryptamine derivative which acts as a selective serotonin receptor 5-HT1A agonist. It was researched unsuccessfully for the treatment of stroke but remains in use for scientific research.〔Bielenberg GW, Burkhardt M. 5-hydroxytryptamine1A agonists. A new therapeutic principle for stroke treatment. ''Stroke''. 1990 Dec;21(12 Suppl):IV161-3. PMID 2148035〕〔Critchley MA, Njung'e K, Handley SL. Actions and some interactions of 5-HT1A ligands in the elevated X-maze and effects of dorsal raphe lesions. ''Psychopharmacology (Berlin)''. 1992;106(4):484-90. PMID 1533721〕〔Canto de Souza A, Nunes de Souza RL, Péla IR, Graeff FG. High intensity social conflict in the Swiss albino mouse induces analgesia modulated by 5-HT1A receptors. ''Pharmacology, Biochemistry and Behavior''. 1997 Mar;56(3):481-6. PMID 9077586〕〔Canto-de-Souza A, Nunes de Souza RL, Pelá IR, Graeff FG. Involvement of the midbrain periaqueductal gray 5-HT1A receptors in social conflict induced analgesia in mice. ''European Journal of Pharmacology''. 1998 Mar 26;345(3):253-6. PMID 9592023〕
==See also==

* 8-OH-DPAT
* RDS-127
* RU-28306
* LY-293,284

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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